in vitro cytotoxicity of plantago australis ethanol extract used as an anti-inflammatory for the treatment of oral pathologies

نویسندگان

isadora luana flores department of semiology and clinics, post-graduate program in dentistry, dental school, federal university of pelotas, pelotas, rs, brazil

thiago de oliveira gamba department of oral diagnosis, post graduate program in oral radiology, piracicaba dental school, university of campinas, piracicaba, sp, brazil

rodrigo varella de carvalho school of dentistry, meridional faculty (imed), passo fundo, rs, brazil

rafael guerra lund post-graduate program in dentistry, dental school, federal university of pelotas, pelotas, rs, brazil; post-graduate program in dentistry, dental school, federal university of pelotas, pelotas, rio grande do sul, brazil. tel/fax: +55-5332226690

چکیده

results in vitro analysis showed that the greater the concentration of the extract, the greater the cytotoxicity. conclusions the crude extract of p. australis might be cytotoxic at high concentrations as evaluated against the cell line. materials and methods the mtt cytotoxicity assay was performed on a 3t3 mouse fibroblast cell line to measure the in vitro cytotoxic activity of the crude formulation. objectives the main objective is to assess in vitro the cytotoxicity of the crude ethanolic extract of p. australis at different concentrations. background plantago australis lam. is a plant native to southern brazil largely used to reduce inflammation and improve the healing process. interestingly, though, there are no previous studies evaluating the cytotoxicity of its ethanolic extract.

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عنوان ژورنال:
jentashapir journal of health research

جلد ۷، شماره ۱، صفحات ۰-۰

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